邹瑞芬个人简介

时间:2018-04-03浏览:10

邹瑞芬个人简介



基本信息:

性别:女

学历:博士研究生

职称:讲师

邮箱:zouruifen@mail.jnmc.edu.cn

教育背景

2016.09 – 2020.09 中国科学院大学中国科学院宁波材料技术与工程研究所 材料物理与化学专业 博士研究生

2010.09 – 2013.07 中国科学院大学中国科学院宁波材料技术与工程研究所化学工程专业 硕士研究生

2006.09 – 2010.07 长沙理工大学 化学专业 理学学士

工作经历

2023.09  济宁医学院太阳成集团tyc33455cc讲师

2020.12 – 2023.02 中国科学院宁波材料技术与工程研究所(流动站)/慈溪市人民医院(工作站) 博士后

2015.12 – 2016.08 中国科学院宁波材料技术与工程研究所纳米生物材料研究组高级助理

教授课程  

生物化学、生物化学实验、生物分离工程、生物分离工程实验等。

研究领域及方向:

酶响应型分子探针的构建及生物相关标志物(肿瘤/细菌/炎症)的精准诊治研究

荣誉、奖励及主要社会兼职:

1. 2021年,中国科学院宁波材料技术与工程研究所“优秀共产党员”

2. 2018年,中国科学院大学“三好学生”

3. 2010年,长沙理工大学 优秀毕业生、优秀毕业论文

主持科研基金项目:

1. 中国博士后科学基金:γ-GGT响应型近红外有机荧光小分子探针的合成及其在淋巴结转移食管鳞癌中的成像研究(结题,2021-012022-12

2. 浙江省自然科学基金,探索项目/探索青年:MRI-荧光双模态酶响应纳米探针的构建及其在食管鳞癌中的成像研究(在研,2022-012024-12

3. 宁波市自然科学基金,一般项目:新型γ-谷氨酰转肽酶响应型有机荧光小分子探针的合成及其在脑胶质瘤精准成像中的应用研究(在研,2021-042025-03

发表文章 

1. Ruifen Zou, Qiuyu Gong, Zhenzhi Shi, Jianping Zheng*, Jie Xing, Chuang Liu, Zhenqi Jiang and Aiguo Wu*. A ZIF-90 nanoplatform loaded with an enzyme responsive organic small-molecule probe for imaging the hypoxia status of tumor cells, Nanoscale, 2020, 12, 14870.SCI 2, TOP期刊, IF=8.307

2. Qiuyu Gong#, Ruifen Zou#, Jie Xing, Lingchao Xiang, Renshuai Zhang, and Aiguo Wu*. A Ultrasensitive Near-Infrared Fluorescent Probe Reveals Pyroglutamate Aminopeptidase 1 Can Be a New Inflammatory Cytokine, Adv. Sci. 2018, 5, 1700664. (共一,SCI 1, TOP期刊, IF=17.521

3. Jing Xiang#, Ruifen Zou#, Pin Wang, Xinfangzi Wang, Xuefei He, Fang Liu*,Chen Xu*, Aiguo Wu*.Nitroreductase-responsive nanoparticles for in situ fluorescence imaging and synergistic antibacterial therapy of bacterial keratitis. Biomaterials,2024,308:122565.(共一,SCI 1, TOP期刊, IF= 15.304

4. Jing Xiang#, Ruifen Zou#, Yu Jiang, Lingchao Xiang, Fang Liu*, Chen Xu*, and Aiguo Wu*. Harnessing the Potential of a Nitroreductase-Responsive Fluorescent Probe for the Diagnosis of Bacterial Keratitis. Bioconjugate Chem. 2024. 10.1021/acs.bioconjchem.4c00234. (共一,SCI 1, IF= 4.7

5. Ruifen Zou, Zhong Cao*, Ju Lan Zeng, Yun Lin Dai, Li Xian Sun*, Characteristics and Mechanism for Host-Guest Recognition of Isopropanol Vapor Based on Calixarene Supramolecules. Advanced Materials Research, 2011, 239-242:2050-2053. EI

6. Ruifen Zou, Qin OuYang, Xuefei Wang, Yousi Chen, Effect of Finishes on the Structural Transformation of PAN Precursor Fiber during the Pre-Oxidation and Low-Temperature Carbonization Process, Synthetic Fiber in China, 2013, 42(6):1-5. (中文核心)

7. Jie Xing, Qiuyu Gong*, Ruifen Zou, Zihou Li, Yuanzhi Xia, Zhangsen Yu, Yufan Ye, Lingchao, Xiang, Aiguo Wu*. A novel fibroblast activation protein-targeted near-infrared fluorescent off-on probe for cancer cells detection, in vitro and in vivo imaging, Journal of Materials Chemistry B, 2018, 6, 1449-1451. SCI 2, TOP期刊, IF= 7.571

8. Leyong Zeng#, Yuanwei Pan#, Ruifen Zou, Jinchao Zhang, Ying Tian, Zhaogang Teng, Shouju Wang, Wenzhi Ren, Xueshan Xiao, Jichao Zhang, Lili Zhang, Aiguo Li, Guangming Lu*, Aiguo Wu*. 808 nm-excited upconversion nanoprobes with low heating effect for targeted magnetic resonance imaging and high-efficacy photodynamic therapy in HER2-overexpressed breast cancer. Biomaterials, 2016,103, 116-127. SCI 1, TOP期刊, IF= 15.304

9. Xin Qian, Ruifen Zou, Qin OuYang, Xuefei Wang, Yonggang Zhang*, Surface structural evolvement in the conversion of polyacrylonitrileprecursors to carbon fibers, Applied Surface Science, 2015, 327:246-252. SCI 1, TOP期刊, IF=7.392

10. Jie Xing, Qiuyu Gong, Ruifen Zou, Junlie Yao, Lingchao Xiang, Aiguo Wu*, GSH responsive traditional clinical drugs probe for cancer cell fluorescence imaging and therapy, Chinese Chemical Letters, 2023, 34:107786. SCI 1, TOP期刊, IF=8.455

11. Leyong Zeng, Di Wu, Ruifen Zou, Tianxiang Chen, Jinchao Zhang*, Aiguo Wu*. Paramagnetic and Superparamagnetic Inorganic Nanoparticles for T1-Weighted Magnetic Resonance Imaging. Current Medicinal Chemistry, 2017, 24, 1-17. SCI 3, IF= 4.74

12. Jie Xing, Qiuyu Gong*, Renshuai Zhang, Shan Sun, Ruifen Zou, Aiguo Wu*. A novel non-enzymatic hydrolytic probe for dipeptidyl peptidase IV specific recognition and imaging, Chem. Commun., 2018, 54, 8773. SCI 2, TOP期刊, IF= 6.065

13. Chuang Liu, Jie Xing, Ozioma Udochukwu Akakuru, Lijia Luo, Shan Sun, Ruifen Zou, Zhangsen Yu, Qianlan Fang, and Aiguo Wu*, Nanozymes-Engineered Metal-Organic Frameworks for Catalytic Cascades-Enhanced Synergistic Cancer Therapy. Nano Lett, 2019, 19 (8), 5674-5682. SCI 1, TOP期刊, IF= 12.262

14. Kaiwei Xu, Lufei Jin, Liu Xu, Yuchao Zhu, Lu Hong, Chunshu Pan, Yanying Li, Junlie Yao, Ruifen Zou, Weiwei Tang, Jianhua Wang*, Aiguo Wu* and Wenzhi Ren*, IGF1 receptor-targeted black TiO2 nanoprobes for MRI-guided synergetic photothermal-chemotherapy in drug resistant pancreatic tumor, Journal of Nanobiotechnology, 2022, 20:315. SCI 1, TOP期刊, IF=11.509

15. Juan Li, Yang Du, Zhenqi Jiang, Yuchen Tian, Nianxiang Qiu, Yinjie Wang, Muhammad Zubair lqbal, Menying Hu, Ruifen Zou, Lijia Luo, Shiyu Du, Jie Tian*, Aiguo Wu*, Y1 receptor ligand-based nanomicelle as a novel nanoprobe for glioma-targeted imaging and therapy, Nanoscale, 2018, 10, 5845-5851. SCI 2, TOP期刊, IF=8.307

16. Jie Xing, Qiuyu Gong, Ozioma Udochukwu Akakuru, Chuang Liu, Ruifen Zou and Aiguo Wu*, Research advances in integrated theranostic probes for tumor fluorescence visualization and treatment. Nanoscale, 2020, 12(48), 24311-24330. SCI 2, TOP期刊, IF=8.307

17. Ting Xue, Siqi Wang, Guoyu Ou, Yong Li, Huimin Ruan, Zihou Li, Yuanyuan Ma, Ruifen Zou, Jiaoyan Qiu, Zheyu Shen * and Aiguo Wu*, Detection of circulating tumor cells based on improved SERS-active magnetic nanoparticles. Anal. Methods, 2019, 11, 2918. SCI 3, IF= 3.532

18. Jiaoyan Qiu, Ling Fu, Hongsen Wang, Ruifen Zou, Yujie Zhang*, XingLi*, and Aiguo Wu*. Colorimetric detection of Cs+ based on nonmorphological transition mechanism of gold nanopartiles in the presence of Prussian blue. New Journal of Chemistry, 2020, 44, 2241-2246. SCI 3, IF= 3.925

19. Chen Xu, Zihou Li, Ozioma Udochukwu Akakuru, Chunshu Pan, Ruifen Zou, Jianjun Zheng*, Aiguo Wu*, Maltodextrin-conjugated Gd-based MRI contrast agents for specific diagnosis of bacterial infections. ACS Applied Bio Materials, 2021, 4(5), 3762-3772. SCI, IF= 4.6

发表专利

1. 吴爱国、邹瑞芬、龚秋雨,一种化合物、其制备方法及作为荧光探针的应用申请号:201711208547.0 (授权时间:2020-11-03

2. 吴爱国、邢洁、龚秋雨、邹瑞芬,化合物I、其制备方法及含有其的荧光探针和应用 申请号:201711170016.7 (授权时间:2020-11-03

3. 吴爱国、陈天翔、马雪华、邹瑞芬Muhammad Zubair Iqbal、项灵超,一种磁性纳米粒子及其制备方法和应用 申请号:201511005964.6 (授权时间:2020-05-08

4. 吴爱国、任文智、邹瑞芬,一种纳米复合材料及其在示踪淋巴结中的应用申请号:201710092810.8

5. 吉振宁、邹瑞芬、张纪庄、李娟、郭咏梅、吴爱国,一种多功能纳米反应器的制备方法及其在CT引导光热增敏自适应放疗系统中的应用 申请号: 202210305009.8

发表专著

1. 邹瑞芬,吴爱国,李娟《肿瘤微环境概论》专著7.2章节撰写(同济大学/同济大学出版社,2022年)